Artigo
A vida sem dor: os pais somente imaginaram que havia algo errado quando viram as feridas em seu filho
Casos raros de neuropatia sensorial e autonômica (HSAN) hereditária são exemplos da importância da presença da sensação dolorosa para a manutenção da integridade física e controle das funções corporais.
Referências:
1. J. L. Bonkowsky et al., "An infant with primary tooth loss and palmar hyperkeratosis: A novel mutation in the NTRK1 gene causing congenital insensitivity to pain with anhidrosis," Pediatrics, 112:e237-41, 2003.
2. E. Einarsdottir et al., "A mutation in the nerve growth factor gene (NGFB) causes loss of pain perception," Hum Mol Genet, 13:799-805, 2004.
3. A. Bierhaus et al., "Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily," J Clin Invest, 114:1741-51, 2004.
Referências:
1. J. L. Bonkowsky et al., "An infant with primary tooth loss and palmar hyperkeratosis: A novel mutation in the NTRK1 gene causing congenital insensitivity to pain with anhidrosis," Pediatrics, 112:e237-41, 2003.
2. E. Einarsdottir et al., "A mutation in the nerve growth factor gene (NGFB) causes loss of pain perception," Hum Mol Genet, 13:799-805, 2004.
3. A. Bierhaus et al., "Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily," J Clin Invest, 114:1741-51, 2004.